Auto-immune Disease in the NZB/Bi Mice

children and in children with renal disease. More accurate measurement was possible, particularly if a 4-hour specimen was used rather than an overnight 12-hour specimen. However, there are so many variable errors in any method of estimating cell excretion rates, that the method could well be discarded in paediatric practice. Cell concentration in a random urine specimen is easily estimated, a fresh mid-stream sample being examined in a counting chamber. This test combined with the Hemastix test for blood gives sufficient information for the management of children with renal disease.